What are the early warning signs of age-related macular degeneration (AMD)? In the early stages, patients may notice blurry central vision, wavy lines or difficulty reading. Often, symptoms are dismissed as a normal part of ageing, leading to a delay in asking for help. In some cases, routine eye exams detect macular degeneration before symptoms first appear.
What vision looks like with macular degeneration
What are the symptoms of macular degeneration disease – why is my vision blurry?
The macula is the central part of the retina that deals with fine, high quality vision such as reading or recognising faces. In macular degeneration, the cells in the central retina become damaged and as a result are not able to see as well as they would normally. In the beginning, all patients have dry macular degeneration, which is a wear and tear process within the retina. About 15% of patients will then go on to develop wet macular degeneration, which will require treatment to stop rapid visual loss.
What is the red flag for macular degeneration?
Straight lines appearing ‘wavy’ or distorted is a red flag for the development of wet macular degeneration. This occurs when there is bleeding or fluid leakage in or under the macula and this causes a disorganisation of the very fine cells of the retina. As a result, straight lines will appear distorted or wavy and this is a sign that a patient needs to seek medical attention from their optician or their eye doctor.
Macular degeneration tests and diagnosis
When the patient goes to see their optician or eye doctor, they will receive a thorough examination and further tests to assess the health of the eye. This will include:
- Visual acuity: this is the very common eye test where you will be asked to read letters from the chart. This is normally done with glasses so that the best possible vision is achieved from the eye.
- Dilated Eye Exam: this is where drops are instilled into the eye to dilate the pupil. This will allow thorough examination of the entire retina and the central retina in particular. In the context of macular degeneration, the central retina will be examined in detail for any signs of this condition.
- Amsler grid: this is a very useful test that patients can perform at home to check for any distortions in the vision of straight lines
- Optical Coherence Tomography (OCT): this is a very fast and painless test that can give detailed images of the macula and will give an instant diagnosis of whether a patient has macular degeneration or not
- Fluorescein Angiography (for wet AMD): this test involves injecting dye into a vein and then taking photographs of the eye. The test is done less often these days but can be useful in some patients where there is doubt about the exact diagnosis
Wet Macular Degeneration and Dry Macular Degeneration
What type of macular degeneration do I have – dry or wet?
Everyone with macular degeneration has the dry form. This form develops initially as wear and tear changes in the retina and may be there in patients who don’t have any symptoms at all. As dry macular degeneration progresses, patients may notice increasing blurring of their central vision. In about 15% of patients, wet macular degeneration can develop on top of this. The distinction is very important as wet macular degeneration requires urgent treatment with injections into the eye.
How do I know if my macular degeneration is getting worse?
It is very common for patients who have been diagnosed with macular degeneration to want to know how far their condition has progressed. This is not an easy question to answer as it will require several different tests to establish the level of the condition. One of these tests will be a simple vision test on the chart. Another common test is an OCT scan of the retina. Doctors generally regard advanced AMD to be composed of either wet macular degeneration or geographic atrophy. Nevertheless, both forms of the disease can be present in patients with quite good vision.
Is macular degeneration permanent?
In general, we don’t have many good treatments for dry macular degeneration, and we certainly don’t have many good treatments that can reverse the condition. Hence many treatments at present are designed to reduce the risk of progression of dry macular degeneration. In the context of wet macular degeneration, injection treatment can certainly lead to reversal of bleeding and fluid leakage and can improve the vision.
Macular Degeneration Treatment
Dry AMD (Early to Intermediate):
Unfortunately, there is no cure for dry macular degeneration. However, AREDS2 supplementations in the form of vitamin and antioxidant supplements has been shown to reduce the risk of progression in some suitable patients. It is certainly important to undertake certain lifestyle changes such as stopping smoking as this is very closely linked to progression of macular degeneration.
Wet AMD:
In patients with wet macular degeneration, by far the most effective therapy that we have is injections into the eye using drugs that target the molecule that drives the disease. This will not be a single injection but will be a course of injections that initially start every month and then become less frequent. A small number of patients may benefit from having extra laser treatment to reduce their injection frequency.
How often will I need injections or follow-ups?
All patients with wet macular degeneration will generally start with monthly injections. These will continue for three to four months after which most patients will then be able to have injections less frequently. Initially the injection intervals may be every two months or every three months. As time goes on the interval may be further extended. The aim is always to try and stop treatment, although this is not always possible. Stopping treatment needs to be done in a controlled way to ensure there is no damage to the vision. A common way of doing this is to wait until patients need 3 consecutive injections every three months. One injection can then be deferred with very close observation of the eye to see whether the condition recurs.
Do injections for macular degeneration improve vision?
Although injection treatment for wet macular degeneration is designed to stabilise the vision and stop any further deterioration, the average patient does get an improvement in their vision. This improvement can be significant in some patients, but it is difficult to predict until the treatment is given and the outcome is observed. Certainly we know from the days when we did not have injection treatment that without treatment patients generally lose vision relatively quickly.
Macular degeneration injection side effects
The main side effect that we worry about is the very small risk of serious eye infection. This can damage the vision permanently so we go to very great lengths to prevent it happening by using antiseptic and a sterile technique for treatment. If a serious eye infection happens, it will need urgent treatment with antibiotics. Nevertheless, damage to the vision may be permanent. The risk of this infection is less than one in 1,000. Much more common side effects include a scratchy sore eye for the first day after the injection and a good way to treat this is with lots of lubricating dry eye drops such as Hycosan Original four times daily.
Ongoing monitoring of macular degeneration
Patients with macular degeneration should have ongoing monitoring. For patients with dry macular degeneration, an Amsler grid should be used at home once a week for each eye separately. Patients need to stay alert for any new symptoms, particularly distortion of straight lines on the Amsler grid. Patients with wet macular degeneration will be monitored very closely as they undergo injection treatment to determine the response to treatment and to check the fellow eye for any sign of wet macular degeneration.
How will I know if my macular degeneration is getting worse?
If you have been diagnosed with macular degeneration, you will know that your condition is getting worse if your vision is more blurred or if you notice any increase in distortion of straight lines appearing wavy. It is important to have regular eye checks to ensure the macular degeneration is monitored and to exclude any other conditions that may be affecting the vision and that may require treatment.
What should I do if I notice a sudden change in vision?
If you notice a sudden change in the vision, it is important not to ignore this and to seek medical attention. Opticians can be a very useful first port of call as long as they have an eye test appointment available within 24-48 hours. If this is not available, patients should see their nearest Eye Casualty who will be able to examine the eye and diagnose the problem.
Vision rehabilitation and coping with vision loss
There is a great deal to offer patients to help them manage with visual loss. Patients can be referred to Low Vision clinics who are able to provide magnifying glasses, large print materials and new technologies to help patients remain independent. Getting in touch with vision support groups such as the Macula Society can help with emotional support and guidance also.
Can I drive with macular degeneration ?
In order to drive a car safely in the UK, the DVLA state that a person must be able to read a number plate with both eyes open at a distance of 20 metres. Your optician or eye doctor will be able to help you determine whether your vision is good enough to meet these criteria.
What devices can help me with reading or recognising faces?
It is important that all patients with macular degeneration have up-to-date eye tests and up-to-date glasses to help make the most of their vision. When reading it is important to have good lighting to make this easier. Magnifying glasses can help a great deal in this regard also. Modern technologies such as the use of tablets means that it is much easier to enlarge texts, and some patients also notice that reversing the text such that white letters are presented on a black background can make reading easier.
How can I maintain independence with low vision?
Patients with low vision can remain independent and certainly do not need to leave their current home. The support of Eye Clinic Liaison Officers as well as social services can help make adaptations to help patients remain independent. Being registered as sight impaired or severely sight impaired can open up a whole range of services to ensure patients are supported in their activities of daily living.
Support for macular degeneration
Patients with visual loss can naturally become quite anxious or depressed and therefore emphasising the importance of good mental health is essential. For this, there is a whole range of support groups and health professionals who can empower patients and reduce their feeling of isolation. Involving the family and other caregivers is crucial for ongoing care and emotional well-being.
How can my family help me manage this condition?
Family and friends are essential for patients with macular degeneration. The condition can cause anxiety and it is important that patients feel they have the support or family and friends in this regard. Family and friends can provide emotional support and they can also provide more practical support such as in helping bring patients to their appointments. Having family and friends attend appointments can help patients feel supported as they manage their diagnosis.
Are there clinical trials or new treatments available for macular degeneration?
New treatments are constantly being trialled for macular degeneration. In the context of wet macular degeneration, longer lasting injections are being investigated to help reduce the burden of treatment for patients. For dry macular degeneration, treatments are being investigated for reducing the progression of the condition or even for reversing the disease. It is a good idea to keep abreast of new developments by asking your eye health professional.
If you are experiencing the early warning signs of age-related macular degeneration (AMD), book an appointment with me today. Call 020 3953 4999 or email secretary@zaidshalchi.co.uk.